مدیریت مرکز

مدیریت آزمایشگاه: دکتر سید محمد باقر هاشمی - سوته

  • متخصص ژنتیک پزشکی از انگلستان
  • دانشیار ژنتیک انسانی
  • گروه بیوشیمی، بیوفیزیک و ژنتیک، دانشکده پزشکی
  • دانشگاه علوم پزشکی مازندران

آقای دکتر سید محمد باقر هاشمی-سوته، دوره کارشناسی زیست شناسی را از دانشگاه شیراز و دوره کارشناسی ارشد ژنتیک انسانی را در دانشگاه علوم پزشکی تهران گذرانده است، آقای دکتر هاشمی، از اولین دوره دانشجویان رشته ژنتیک انسانی در کشور و به عنوان اولین فارغ التحصیل این رشته محسوب می گردند. آقای دکتر هاشمی دوره دکتری (PhD)و پسا دکتری (Post-doctoral) خود را در دانشگاه شفیلد، کشور انگلستان گذرانده است و از سال 1373 تاکنون به عنوان عضو هیئت علمی دانشگاه علوم پزشکی مازندران و با رتبه دانشیاری مشغول بکار می باشند و حاصل این فعالیت، آموزش ژنتیک پزشکی به هزاران دانشجوی رشته های مختلف علوم پزشکی می باشد. همچنین مقالات علمی بین المللی و داخلی متعددی تاکنون در زمینه بیماری های مختلف ارثی به چاپ رسانده است و عضو مراکز مختلف تحقیقاتی این دانشگاه می باشند.

عضویت در:

  • مرکز تحقیقات بیولوژی سلولی و مولکولی
  • مرکز تحقیقات ایمنوژنتیک
  • مرکز تحقیقات بیماری های کبد و گوارش
  • مرکز تحقیقات توکسوپلاسما
  • عضو کار گروه کشوری سلول های بنیادی و ژنتیک معاونت علمی نهاد ریاست جمهوری
  • عضو انجمن پزشکی مولکولی و کمیته تخصصی تشخیص های قبل از تولد (PND)
  • موسس و مسئول فنی آزمایشگاه تخصصی نوین ژنتیک ، از سال 1388
  • (اولین آزمایشگاه تشخیصی و تخصصی در زمینه بیماری های ارثی در استان مازندران)

 

لینک صفحه دکتر هاشمی در  Google Scholar

https://scholar.google.com/citations?hl=en&user=WB81zeUAAAAJ&view_op=list_works

 

قسمتی از مقالات دکتر سید محمد باقر هاشمی

Phenotype and genotype of a cohort of families historically diagnosed with type 1 von Willebrand disease in the European study, Molecular and Clinical Markers for the Diagnosis …

A Goodeve, J Eikenboom, G Castaman, F Rodeghiero, AB Federici, ...

Blood 109 (1), 112-121

 

Identification of Candida species using PCR-RFLP in cancer patients in Iran

T Shokohi, MBH Soteh, ZS Pouri, MT Hedayati, S Mayahi

Indian journal of medical microbiology 28 (2), 147

 

Haptoglobin polymorphism in individuals with type 2 diabetic microangiopathy

AA Amiri, MB Hashemi-Soteh, MR Haghshenas, F Daneshvar, A Rastegar, ...

North American journal of medical sciences 5 (9), 529

 

Effect of Mesenchymal Stem Cells on Doxorubicin-Induced Fibrosis

SM Gorji, AAK Malekshah, MB Hashemi-Soteh, A Rafiei, K Parivar, ...

Cell Journal (Yakhteh) 14

 

Assessment of demographic, clinical and laboratory status of patients with thalassemia major and intermedia referred to thalassemia research center in Sari, Iran, during 2007-2009.

H Karami, M Kowsaryan, K Vahidshahi, S Shahmohammadi, M Mahdavi, ...

Pejouhandeh 15 (4)

 

The role of clinical response to metformin in patients newly diagnosed with type 2 diabetes: a monotherapy study

A Mahrooz, H Parsanasab, MB Hashemi-Soteh, Z Kashi, A Bahar, ...

Clinical and experimental medicine 15 (2), 159-165

 

Detection of invasive aspergillosis in bone marrow transplant recipients using real-time PCR

M Nabili, T Shokohi, G Janbabaie, MB Hashemi-Soteh, K Ali-Moghaddam, ...

Journal of global infectious diseases 5 (2), 68

 

Molecular Characterization of Echinococcus granulosus from Hydatid Cysts Isolated from Human and Animals in Golestan Province, North of Iran

S Gholami, M Sosari, M Fakhar, M Sharif, A Daryani, MB Hashemi, ...

Iranian Journal of Parasitology 7 (4), 8

 

Mutational analysis of the von Willebrand factor gene in type 1 von Willebrand disease using conformation sensitive gel electrophoresis: a comparison of fluorescent and manual …

MH Soteh, IR Peake, L Marsden, J Anson, J Batlle, D Meyer, E Fressinaud, ...

haematologica 92 (4), 550-553

 

R-carrying genotypes of serum paraoxonase (PON1) 192 polymorphism and higher activity ratio are related to susceptibility against ischemic stroke

A Mahrooz, G Gohari, MB Hashemi, M Zargari, H Musavi, M Abedini, ...

 

R-carrying genotypes of serum paraoxonase (PON1) 192 polymorphism and higher activity ratio are related to susceptibility against ischemic stroke

A Mahrooz, G Gohari, MB Hashemi, M Zargari, H Musavi, M Abedini, ...

Molecular biology reports 39 (12), 11177-11185

 

The variant organic cation transporter 2 (OCT2)–T201M contribute to changes in insulin resistance in patients with type 2 diabetes treated with metformin

Z Kashi, P Masoumi, A Mahrooz, MB Hashemi-Soteh, A Bahar, A Alizadeh

Diabetes research and clinical practice 108 (1), 78-83

 

HLA-G5 and G7 Isoforms in Pregnant Women.

S Abediankenari, F Farzad, Z Rahmani, MB Hashemi-Soteh

Iranian Journal of Allergy, Asthma and Immunology, 217-221

 

Molecular identification of Candida albicans isolated from the oncology patients at four university hospitals in Mazandaran province (2005-6)

M Fatahi, T Shokohi, H Sooteh, MT Hedayati, A Okhovatian, A Tamadoni, ...

Journal of Mazandaran University of Medical Sciences 17 (61), 1-11

 

Evaluation of the immune response in BALB/c mice induced by a novel DNA vaccine expressing GRA14 against Toxoplasma gondii

E Ahmadpour, S Sarvi, MB Hashemi Soteh, M Sharif, MT Rahimi, ...

Parasite immunology 39 (4), e12419

 

Aldose reductase C-106T gene polymorphism in type 2 diabetics with microangiopathy in Iranian individuals

MRS Rezaee, AA Amiri, MB Hashemi-Soteh, F Daneshvar, ...

Indian journal of endocrinology and metabolism 19 (1), 95

 

Prevalence of hemoglobinopathies in premarriage individuals referred to Babolsar, Iran (2006-09).

F Valizadeh, A Mousavi, MB Hashemi-Soteh

Journal of Gorgan University of Medical Sciences 14 (1)

 

Enhancing immune responses to a DNA vaccine encoding Toxoplasma gondii GRA14 by calcium phosphate nanoparticles as an adjuvant

E Ahmadpour, S Sarvi, MBH Soteh, M Sharif, MT Rahimi, R Valadan, ...

Immunology letters 185, 40-47

 

Identification of Malassezia Species isolated from patients with pityriasis versicolor and seborrhoeic dermatitis by PCR-RFLP

T Shokohi, Z Hajheidari, A Barzgar, H Sooteh, MT Hedayati, SR Aghili, ...

Journal of Mazandaran University of Medical Sciences 18 (66), 51-62

 

Frequencies of three CYP2D6 nonfunctional alleles (CYP2D6* 3,* 4, and* 6) within an Iranian population (Mazandaran)

SMB Hashemi-Soteh, F Sarzare, F Merat, E Salehifar, MR Shiran

Genetic testing and molecular biomarkers 15 (11), 821-825

 

Assessment of coagulation state and its related factors in thalassemia intermedia patients referred to thalassemia research center at Booali Sina Hospital Sari/IR Iran in 2007

H Karami, K Vahidshahi, M Kosarian, H Karami, S Shahmohammadi, ...

Pakistan Journal of Biological Sciences 13 (9), 448

 

The role of HLA-G4 and G5 in threatened-abortion women

F Farzad, S Abediankenari, Z Rahmani, MB Hashemi-Soteh, ...

Journal of Mazandaran University of Medical Sciences 23 (106), 2-10

 

Biochemical mechanisms of dose-dependent cytotoxicity and ROS-mediated apoptosis induced by lead sulfide/graphene oxide quantum dots for potential bioimaging applications

M Ayoubi, P Naserzadeh, MT Hashemi, MR Rostami, E Tamjid, ...

Scientific reports 7 (1), 12896

 

Quantification and Optimization of Aspergillus Fumigatus DNA Detection in Blood Sample Using Real Time PCR

M Nabili, T Shokohi, MBH Soteh, GJ Babaie, SR Aghili, Z Hoseinikhah

J Mazandaran Univ Med Sci 2011, 20(80): 34-43 20 (80), 34-43

 

H1299R in coagulation Factor V and Glu429Ala in MTHFR genes in recurrent pregnancy loss in Sari, Mazandaran

N Arabkhazaeli, K Ghanaat, MB Hashemi-Soteh

International journal of reproductive biomedicine 14 (5), 329

 

Effects of sodium acetate and nisin on microbial and chemical changes and fatty acid composition of grass carp Ctenopharyngodon idella during refrigeration storage

MR Ghomi, M Nikoo, Z Heshmatipour, JA Amir, M Ovissipour, M Hashemi, ...

J. Food Saf

 

The study of relationships between β-globin gene mutations in β-thalassaemia patients, in response to hydroxyurea treatment

H Soteh, H Akhavan Niaki, M Kosarian, A Aliasgharian, F Mojtahedzadeh, ...

Journal of Mazandaran University of Medical Sciences 18 (64), 1-10

 

 

Paraoxonase 1 (PON1)-L55M among common variants in the coding region of the paraoxonase gene family may contribute to the glycemic control in type 2 diabetes

A Mahrooz, MB Hashemi-Soteh, M Heydari, R Boorank, F Ramazani, ...

Clinica Chimica Acta 484, 40-46

 

Association between the synonymous variant organic cation transporter 3 (OCT3)-1233G> A and the glycemic response following metformin therapy in patients with type 2 diabetes

SR Hosseyni-Talei, A Mahrooz, MB Hashemi-Soteh, M Ghaffari-Cherati, ...

Iranian journal of basic medical sciences 20 (3), 250

 

The Polymorphic Variants rs3088442 and rs2292334 in the Organic Cation Transporter 3 (OCT3) Gene and Susceptibility Against Type 2 Diabetes: Role of their Interaction

A Mahrooz, A Alizadeh, MB Hashemi-Soteh, M Ghaffari-Cherati, ...

Archives of medical research 48 (2), 162-168

 

The cloning of non-structural-1 (NS1) gene of H9N2 subtype of avian influenza virus in pGEX-4T-1 and pMAL-c2X plasmids and expression in Escherichia coli DH5α strain

R Soleimani, MV Marandi, MB Hashemi-Soteh, F Hemmatzadeh

Advances in Bioscience and Biotechnology 3 (3), 283-289

 

Detection of invasive aspergillosis in patients with hematological malignancy and bone marrow transplant recipients using Real-Time PCR 2009-10. J Global infect Dise. 2013; 5 …

M Nabili, T Shokohi, G Jan Babaei, MB Hashemi Soteh, K Ali Moghaddam, ...

J Burn Care Res 29 (1), 213-221

 

Allele frequency and genotype distribution of a common variant in the 3-untranslated region of the SLC22A3 gene in patients with type 2 diabetes: Association with response to …

M Ghaffari-Cherati, A Mahrooz, MB Hashemi-Soteh, SR Hosseyni-Talei, ...

Journal of research in medical sciences: the official journal of Isfahan …

 

Antimicrobial Effect of Imipenem-Functionalized Fe2O3 Nanoparticles on Pseudomonas aeruginosa Producing Metallo β-lactamases

MR Khataminejad, R Mirnejad, M Sharif, M Hashemi, N Sajadi, V Piranfar

Iranian journal of biotechnology 13 (4), 43

 

Molecular evaluation of hemoglobin D mutations in Mazandaran province, Iran.

MR Mahdavi, P Roshan, N Yousefian, MT Hojjati, MB Hashemi-Soteh

Journal of Gorgan University of Medical Sciences 15 (2)

 

Frequency of Factor V Leiden, Prothrombin G20210 and C667T Mutations in Methylenetetrahydrofolate Reductase in Patients with Beta and Intermediate Thalassemia Compared with …

H Soteh, A Aliasgharian, H Jalali, SN Nejati Fard, M Kosarian, H Karami

Journal of Mazandaran University of Medical Sciences 21 (81), 2-9

 

Effects of limited doses of retinyl palmitate at the critical time of limb morphogenesis in mouse embryos

N Rezaei, MB Soteh, F Rahimi

CSIR

 

Re‐evaluation of three Israeli families initially diagnosed with type 1 von Willebrand disease in light of the ISTH update on von Willebrand factor pathophysiology and …

SMB Hashemi Soteh, J Anson, A Inbal, IR Peake, AC Goodeve

Haemophilia 14 (3), 621-624

 

Evaluation of Co-Segregation Between Bipolar Mood Disorder and Heterozygous Beta-Thalassemia in Patients Originated From Iran

SH Hosseini, WG Saravi, M Zarghami, A Saljughian

Research Journal of Biological Sciences 3 (7), 798-800

 

Teratogenic Effect of Excess Vitamin A on the limb development in mouse embryo

AM N Rezaee, MB Hashemi, AR Khalilian

J Mazandaran Univ Med Sci 11 (31), 16-25

 

Haplotypes inside the beta-globin gene: use as new biomarkers for beta-thalassemia prenatal diagnosis in north of Iran

MB Hashemi-Soteh, SS Mousavi, A Tafazoli

Journal of biomedical science 24 (1), 92

 

A multiplex restriction enzyme-PCR for unequivocal identification and differentiation of Trichostrongylus species in human samples

A Mizani, P Gill, A Daryani, S Sarvi, A Amouei, AB Katrimi, E Soleymani, ...

Acta tropica 173, 180-184

 

Predicting marital commitment on the basis of relationship maintenance behaviors and attachment styles

R Davarniya, M Shakarami, K Zahrakar, B Mohammadi

JOURNAL OF RESEARCH AND HEALTH 6 (2), 247-255

Cloning and sequencing the plasmid encoding dense granule antigen 14 (GRA14) of Toxoplasma gondii RH strain

E Ahmadpour, S Sarvi, A Daryani, M Sharif, MBH Soteh, A Mizani, ...

Journal of Mazandaran University of Medical Sciences 24 (112), 42-49

 

Production of Cyclin D1 specific siRNAs by double strand processing for gene therapy of esophageal squamous cell carcinoma

N Mottaghi-Dastjerdi, M Soltany-Rezaee-Rad, A Ajami, A Rafiei, ...

Research in Molecular Medicine 1 (1), 10-15

 

Paraoxonase Activity to Arylesterase of Serum Paraoxonase (PON1) and the Ratios of the Activities to HDL in Nondiabetic Patients with Ischemic Stroke: a Case-Control Study …

G Gohari, A Mahrooz, H Musavi, M Zargari, MB Hashemi, M Abedini, ...

Journal of Mazandaran University of Medical Sciences 22 (91), 2-9

 

Disorders of Hemostasis-Mutational analysis of the von Willebrand factor gene in type 1 von Willebrand disease using conformation sensitive gel electrophoresis: A comparison of …

MH Soteh, IR Peake, L Marsden, J Anson, J Batlle, D Meyer, E Fressinaud, ...

Haematologica 92 (4), 550

 

The Correlation between Phospholipase C Epsilon (PLCE1) Gene Polymorphisms and Risk of Gastric Adenocarcinoma in Iranian Population

R Shekarriz, S Faghani, A Tafazoli, MB Hashemi-Soteh

International Journal of Hematology-Oncology and Stem Cell Research 13 (3 …

 

Prevalence of IMP and SPM Genes in Clinical Isolatesof Carbapenem Resistant Acinetobacter baumannii in Educational Hospitals of Sari, Iran

Z Norouzi Bazgir, M Ahanjan, MB Hashemi Soteh, H Reza Goli

Journal of Mazandaran University of Medical Sciences 29 (174), 30-41

 

Aetiology of livestock fetal mortality in Mazandaran province, Iran

A Amouei, M Sharif, S Sarvi, RB Nejad, SA Aghayan, MB Hashemi-Soteh, ...

PeerJ 6, e5920

 

Circulating miR-122 and miR-192 as Specific and Sensitive Biomarkers for Drug-Induced Liver Injury with Acetaminophen in Rats

P Jarsiah, M Karami, A Nosrati, A Alizadeh, MB Hashemi-Soteh

Jundishapur Journal of Natural Pharmaceutical Products

 

Detection of CYP2C18 m1, and m2 Alleles within an Iranian Population (Mazandaran) Using Denaturing High-Performance Liquid Chromatography (DHPLC)

A Rafati, P Gill, M Shabani, M Peyrovei, SMB Hashemi-Soteh, MR Shiran

Research in Molecular Medicine 3 (2), 17-21

 

In vitro and in vivo evaluations of three-dimensional hydroxyapatite/silk fibroin nanocomposite scaffolds

Biotechnology and Applied Biochemistry

 

Investigating Factor V Leiden and Prothrombin G20210A Gene Mutation in Relation with Acute Myocardial Infarction

SMJ Hashemi Petroudi, G Janbabai, SMB Hashemi Soteh, R Shekarriz, ...

J Mazandaran Univ Med Sci 24 (117), 21-28

 

Determination ofToxoplasma gondiiParasitic Load in Balb/c Mice Immunized with ESA of RH Strain using Real Time Q-PCR

A Daryani, Y Dadimoghaddam, M Sharif, M Hashemi, H Kalani, S Sarvi, ...

Tropical Medicine & International Health 18

 

A simplified protocol for producing Taq DNA polymerase in biology laboratory

MF Farazmandfar T, Rafiei A *, Hashemi-Sotehoh MB

Research in Molecular Medicine 1 (2), 19-21

 

Frequencies of two CYP2C19 defective alleles (CYP2C19* 2, and* 3) within an Iranian population

N Shahabi-Majd, SMB Hashemi-Soteh, B Habashi, MR Shiran

Research in Molecular Medicine 1 (1), 0-0

 

PCR-RFLP is a useful tool to distinguish between C. dubliniensis and C. albicans in cancer patients in Iran.

B E. Abdel-Fatah, A M. Moharram, AED AH Moubasher, MA Al-Ryani, ...

American Journal of Biochemistry and Molecular Biology 3 (3), 6502-6516

 

Metabolic capacity of CYP2D6 within an Iranian population (Mazandaran Province)

MR Shiran, F Sarzare, F Merat, E Salehifar, AA Moghadamnia, ...

Caspian journal of internal medicine 2 (2), 213

 

PCR-RFLP Is a Useful Tool to Distinguish between C. Dubliniensis and C. Albicans in Cancer Patients in Iran

MB Hashemi Soteh, T Shokohi, Z Saltanatpouri

International Journal of Hematology-Oncology and S, 1-2

 

Prevalence and spectrum of von Willebrand disease in Iran

M SOTEH, M Jazebi, S Ravanbod, H Karami, A Chupan, F Ala

Haemophilia 14, 112-113

 

Effect of Various Concentrations of Glucose on Bovine Cumulus-Oocyte Complexes Maturation, Fertilization and Early Embryonic Development in Vitro

NA REZAEI, SMB Hashemi, R CHIAN

JOURNAL OF KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES (BEHBOOD) 11 (334), 245-256